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Outcomes after common arterial trunk repair: Impact of surgical technique - 14/08/21

Doi : 10.1016/j.acvdsp.2021.06.013 
Neil Derridj, MD, MPH 1, 2, , Olivier Villemain, MD, PhD 1, Babak Khoshnood, PhD 2, Zahra Belhadjer, MD 1, Régis Gaudin, MD 1, Olivier Raisky, MD, PhD 1, Damien Bonnet, MD, PhD 1
1 M3C-Necker–Enfants-malades, AP–HP, Université de Paris, Paris, France 
2 Université de Paris, CRESS, inserm, INRA, 75004 Paris, France 

Corresponding author.

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Resumen

Objectives

To compare the risk of mortality and re-intervention after common arterial trunk (CAT) repair for different surgical techniques, especially for reconstruction of the right ventricle outflow tract (RVOT) with left atrial appendage without a monocusp.

Methods

We retrospectively included patients with repaired CAT who were followed-up at our institution between 2000 and 2018. A Cox proportional-hazards model was used to investigate risk factors on overall survival and freedom from re-intervention in univariable and multivariable analyses.

Results

One hundred and twenty-nine patients were included in the study. The median follow-up was 8.8 years. 15 patients (11.6%) died after the initial repair. The ten-year survival rate was 88.2% with the poorest outcome for CAT type IV (64.3%; P<0.01). In multivariable analysis, coronary anomalies (HR=11.63 [3.84–35.29], P<0.001) and CAT with interrupted aortic arch (HR=6.50 [2.10–20.16], P=0.001) were risk factors for mortality. Initial repair without valvulation of the RVOT was not associated with an increased risk of mortality (HR=0.37 [0.11–1.24], P=0.11). The median age at re-intervention was 3.6 years [7.3 days-13.1 years]. At 10 years, freedom from re-intervention was higher in the group repaired with left atrial appendage compared to the valved conduit group, 73.3% and 17.2% (P<0.001), respectively. In multivariable analysis, using a valved conduit at repair (HR=4.79 [2.45–9.39], P<0.001), truncal valve insufficiency (HR=2.92 [1.62–5.26], P<0.001) and Di George syndrome (HR=2.01 [1.15–3.51], P=0.01) were risk factors for re-intervention.

Conclusion

CAT type IV and coronary anomalies were risk factors for mortality after CAT repair. The RVOT reconstruction technique with left atrial appendage was not associated with neither short- nor middle-term higher post-operative mortality. This technique was also associated with a significant increase in the time to re-intervention when the latter was required.

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Esquema


 Due to the pandemic, this abstract was already published in The Journal of Thoracic and Cardiovascular Surgery, https://doi.org/10.1016/j.jtcvs.2020.10.147.


© 2021  Publicado por Elsevier Masson SAS.
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Vol 13 - N° 4

P. 276-277 - septembre 2021 Regresar al número
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