Metabolic iron disorder after liver transplant: Hereditary hemochromatosis in a pediatric recipient of a pediatric donor with unknown HFE C282Y homozygous mutation - 22/11/20
Doi : 10.1016/j.clinre.2020.04.009
Laurent Monino a, ⁎ 
, Raymond Reding b, Mina Komuta c, Géraldine Dahlqvist a, b
, Raymond Reding b, Mina Komuta c, Géraldine Dahlqvist a, b a Service d’Hépatogastroentérologie adulte, Cliniques universitaires Saint-Luc, avenue Hippocrate 10, Bruxelles, Belgique
b Service de Chirurgie et Transplantation abdominale, Cliniques universitaires Saint-Luc, Bruxelles, Belgique
c Service d’anatomopathologie, Cliniques universitaires Saint-Luc, Bruxelles, Belgique
⁎Corresponding author.
Summary |
We report a case of an iron overload syndrome twenty years after a liver transplantation in a patient without feature for secondary iron overload. The diagnosis of hemochromatosis with homozygous mutationC282Y in the graft was made possible with liver biopsy, using real-time PCR technique with Light-Cycler 480. Our case suggests that in case of iron overload syndrome after liver transplantation we can perform a liver biopsy with real-time PCR technique that allows us to search for the mutation of the HFE.
El texto completo de este artículo está disponible en PDF.Abbreviations : HH, MRI, PCR
Esquema
© 2020
The Author(s). Publicado por Elsevier Masson SAS. Todos los derechos reservados.
Vol 44 - N° 6
P. e129-e131 - novembre 2020 Regresar al número
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