Oral Hypersensitivity Reactions - 05/09/20

Doi : 10.1016/j.det.2020.05.007

Jacob P. Reinhart, MD ^a,^⁎ , Eric T. Stoopler, DMD, FDSRCS, FDSRCPS ^b, Glen H. Crawford, MD ^c
^a U.S. Navy, San Diego, CA, USA
^b Department of Oral Medicine, University of Pennsylvania, Penn Dental Medicine, 240 South 40th Street, Room 206, Schattner Building, Philadelphia, PA 19104, USA
^c Department of Dermatology, University of Pennsylvania, 822 Pine Street Suite 2A, Philadelphia, PA 19107, USA

^∗Corresponding author. Penn Dental Medicine, 240 South 40th Street, Room 206, Schattner Building, Philadelphia, PA 19104.Penn Dental Medicine240 South 40th Street, Room 206, Schattner BuildingPhiladelphiaPA19104

Resumen

Allergic contact hypersensitivity reactions of the oral mucosa pose a significant medical concern for some patients. Oral hypersensitivity reactions can result from a vast number of allergenic chemicals, but occur commonly from dental materials, flavorings, and preservatives. Clinical presentation is varied and often overlaps with other oral conditions, complicating their diagnosis and management. The most common clinical entities associated with oral hypersensitivity reactions are oral lichenoid reactions and allergic contact cheilitis. In addition to reviewing these conditions and their most common corresponding allergens, this article summarizes the pathogenesis of oral hypersensitivity reactions and addresses patch testing pearls.

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Keywords : Hypersensitivity reaction, Allergic contact stomatitis, Oral mucosa, Dental restorations, Patch testing, Oral lichenoid reactions