Oral Biopsy Techniques - 05/09/20

Doi : 10.1016/j.det.2020.05.003

Rabie M. Shanti, DMD, MD ^a,^⁎ , Takako Tanaka, DDS, FDS, RCSEd ^b, David C. Stanton, DMD, MD ^c,^d,^e
^a Department of Otorhinolaryngology/Head and Neck Surgery, University of Pennsylvania Health System, 3400 Civic Center Boulevard, 4th Floor, South Pavilion, Philadelphia, PA 19104, USA
^b Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, Philadelphia, PA 19104, USA
^c Oral & Maxillofacial Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA
^d Oral & Maxillofacial Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA
^e Department of Oral & Maxillofacial Surgery, Perelman Center, 4th Floor, South Pavilion, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA

^∗Corresponding author.

Resumen

Squamous cell carcinoma makes up 90% of cases of oral cancer. However, a myriad of premalignant, inflammatory, and immune-based conditions can manifest as oral mucosal lesions. Biopsy of these lesions shares many of the principles of cutaneous lesions. Biopsy of oral mucosal lesions is a procedure that is safely performed in most cases in the outpatient ambulatory setting using local anesthesia. Special considerations should be taken depending on the presumed diagnosis based on physical examination. Its clinical relevance depends on a sound clinicopathologic assessment of the patient’s condition. This article reviews specific considerations for biopsy of oral mucosal lesions.

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Keywords : Oral biopsy, Lip biopsy, Oral cancer, Oral dysplasia, Leukoplakia