Lung Function Testing in Chronic Obstructive Pulmonary Disease - 13/08/20

Doi : 10.1016/j.ccm.2020.06.004

J. Alberto Neder, MD, PhD, FRCP(C), FERS ^a, Juan P. de-Torres, MD, PhD ^a, Kathryn M. Milne, MD FRCP(C) ^a,^b, Denis E. O'Donnell, MD, FRCP(I), FRCP(C), FERS ^a,^⁎
^a Division of Respiratory Medicine, Department of Medicine, Kingston Health Science Center, Queen’s University, Richardson House, 102 Stuart Street, Kingston, Ontario K7L 2V6, Canada
^b Clinician Investigator Program, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

^∗Corresponding author. Kingston Health Science Center, Queen’s University, Richardson House, 102 Stuart Street, Kingston, Ontario K7L 2V6, Canada.Kingston Health Science CenterQueen’s UniversityRichardson House102 Stuart StreetKingstonOntarioK7L 2V6Canada

Resumen

Lung function testing has undisputed value in the comprehensive assessment and individualized management of chronic obstructive pulmonary disease, a pathologic condition in which a functional abnormality, poorly reversible expiratory airway obstruction, is at the core of its definition. After an overview of the physiologic underpinnings of the disease, the authors outline the role of lung function testing in this disease, including diagnosis, assessment of severity, and indication for and responses to pharmacologic and nonpharmacologic interventions. They discuss the current controversies surrounding test interpretation with these purposes in mind and provide balanced recommendations to optimize their usefulness in different clinical scenarios.

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Keywords : Lung function, Dyspnea, COPD, Exertion, Diagnosis, Pulmonary function tests