The effect of mupirocin dressings on postoperative surgical site infections in elective colorectal surgery: A prospective, randomized controlled trial - 24/05/19
Abstract |
Background |
Surgical site infections (SSIs) are the most common nosocomial infection among surgical patients. We hypothesized that mupirocin ointment would decrease SSI rates compared to standard surgical dressings in patients undergoing colorectal surgery.
Methods |
A prospective randomized controlled trial was performed, including patients undergoing elective open and minimally invasive colorectal surgery. Patients were randomized 1:1 to receive standard gauze dressings or mupirocin ointment (2%) dressings. The primary outcome was incisional SSI at 30 days postoperative.
Results |
A total of 192 patients were enrolled; 150 underwent randomization: 75 to the mupirocin arm, and 75 to the standard gauze dressing arm. Three SSIs occurred; one (1%) in the mupirocin group, and two (3%) in the standard gauze group (P = 0.560). There was no significant difference between standard gauze dressings and mupirocin dressings.
Conclusion |
Mupirocin (2%) ointment failed to show a benefit compared to standard dressings for postoperative SSI.
El texto completo de este artículo está disponible en PDF.Highlights |
• | Colorectal SSIs are a significant cause of morbidity and mortality. |
• | A prospective randomized study compared SSI rates with mupirocin and gauze dressings. |
• | There was no difference in SSI rate between mupirocin and standard gauze dressings. |
Resumen |
Colorectal surgical site infections are a significant cause of morbidity and mortality. We performed a prospective, randomized controlled trial to investigate the SSI rates between mupirocin ointment and gauze compared to gauze dressings alone. There was no difference in SSI rate between mupirocin dressings and standard gauze dressings.
El texto completo de este artículo está disponible en PDF.Keywords : Surgical site infection, Mupirocin, Wound dressing, Randomized trial
Esquema
Vol 217 - N° 6
P. 1083-1088 - juin 2019 Regresar al número
Artículo precedente
- Acute hyperglycemia increases sepsis related glycocalyx degradation and endothelial cellular injury: A microfluidic study
- Lawrence N. Diebel, David M. Liberati, Jonathan V. Martin
- Reduction of surgical site infections in colorectal surgery: A 10-year experience from an independent academic medical center
- Nolan J. Rudder, Andrew J. Borgert, Kara J. Kallies, Travis J. Smith, Stephen B. Shapiro
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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