Burn injury mortality in patients with preexisting and new onset renal disease - 13/06/18
Abstract |
Introduction |
We sought to examine the impact of preexisting and new onset renal disease on burn injury mortality.
Methods |
Retrospective analysis of patients admitted to a regional burn center from 2002-2012 was performed. Variables analyzed included demographics, burn mechanism, inhalation injury status, and % TBSA. Poisson regression was performed to estimate risk of in-hospital burn mortality.
Results |
There were a total of 7640 patients over the study period. The adjusted 60-day risk of in-hospital mortality in patients with preexisting renal disease (PRD was 3 times higher compared to patients with no preexisting renal disease (IRR = 3.22, 95% CI = 1.26–8.25). The adjusted 60-day risk of mortality is 2 times higher for patients with new onset renal disease compared to those without (IRR = 2.11, 95% CI = 1.55–2.87).
Conclusion |
Preexisting and new onset renal disease results in a significantly higher risk of mortality following burn injury compared to patients without renal disease. Prevention of new onset renal injury and careful management of patients with preexisting renal disease to prevent exacerbation should be pursued.
El texto completo de este artículo está disponible en PDF.Highlights |
• | Acute kidney injury is a common after burn injury. |
• | Acute kidney injury confers two-fold increase in mortality following burn injury. |
• | Pre-existing renal disease leads to three-fold increased burn mortality. |
• | Prevention of new onset renal injury and careful management of patients with preexisting renal disease is mandatory. |
Keywords : Burn injury, Renal disease, Acute kidney injury, Chronic renal disease, Burn mortality
Esquema
Vol 215 - N° 6
P. 1011-1015 - juin 2018 Regresar al número
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