Sarcopenia is not associated with morbidity, mortality, or recurrence after esophagectomy for cancer - 25/04/18
, James P. Dolan a, ⁎ , Elizabeth N. Dewey a , Alexander R. Guimaraes b , Brandon H. Tieu a , Paul H. Schipper a , John G. Hunter a Abstract |
Background |
Sarcopenia is associated with increased morbidity and mortality in hepatic, pancreatic and colorectal cancer. We examined the effect of sarcopenia on morbidity, mortality, and recurrence after resection for esophageal cancer.
Methods |
Retrospective review of consecutive esophagectomies from 2010 to 2015. Computed tomography studies were analyzed for sarcopenia. Morbidity was analyzed using Fischer's test and survival data with Kaplan Meier curves.
Results |
The sarcopenic group (n = 127) had lower BMI, later stage disease, and higher incidence of neoadjuvant radiation than those without sarcopenia (n = 46). There were no differences in morbidity or mortality between the groups (p = .75 and p = .31, respectively). Mean length of stay was similar (p = .70). Disease free and overall survival were similar (p = .20 and p = .39, respectively).
Conclusion |
There is no association between sarcopenia and increased morbidity, mortality and disease-free survival in patients undergoing esophagectomy for cancer. Sarcopenia in esophageal cancer may not portend worse outcomes that have been reported in other solid tumors.
El texto completo de este artículo está disponible en PDF.Highlights |
• | Sarcopenia is highly prevalent in our population of esophageal cancer patients. |
• | Sarcopenia is not associated with increased morbidity after esophagectomy. |
• | Sarcopenia is not associated with decreased disease-free or overall survival after esophagectomy for cancer. |
Keywords : Sarcopenia, Esophageal cancer, Recurrence, Esophagectomy, Outcomes
Esquema
Vol 215 - N° 5
P. 813-817 - mai 2018 Regresar al número
Artículo precedente
- Discussion of “Patient navigation reduces time to care for patients with breast symptoms and abnormal screening mammograms”
- J. David Beatty
- Discussion of “Sarcopenia is not associated with morbidity, mortality, or recurrence after esophagectomy for cancer”
- Ralph W. Aye MD
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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