Dual energy computed tomography should be a first line preoperative localization imaging test for primary hyperparathyroidism patients - 25/04/18
Abstract |
Background |
The objective of this study was to evaluate the performance of dual-energy computed tomography (DECT) for preoperative parathyroid tumor (PT) localization in primary hyperparathyroid (PHP) patients.
Methods |
A retrospective review was carried out of the medical records of all PHP patients who underwent ultrasound (US), Tc-99m sestamibi noncontrast single photon emission computed tomography (CT-MIBI), DECT and parathyroidectomy at a single center.
Results |
The sensitivities and accuracies for preoperative PT localization in the 97 patient study population were: US 40% and 93%, CT-MIBI 64.0% and 97%, and DECT 84% and 96%, respectively. In the one third of the study population that did not localize preoperatively with CT-MIBI and US, DECT correctly localized a PT in 21 cases (66%). DE-CT and US correctly localized a PT in 86% of cases, and only 5 (8%) of the cases that were accurately localized by a combination of CT-MIBI and US were not identified by DE-CT.
Conclusions |
DECT should be utilized as a first line preoperative PT localization study in PHP patients, and is also a sensitive salvage localization test.
El texto completo de este artículo está disponible en PDF.Highlights |
• | DECT is more sensitive than CT-MIBI or US for parathyroid localization. |
• | DECT is as sensitive and accurate as 4D-CT but has a lower patient radiation dose. |
• | DECT is also useful for salvage preoperative parathyroid localization. |
• | DECT should be utilized as a first line imaging test for parathyroid localization. |
Keywords : Primary hyperparathyroidism, Dual energy CT, Ultrasound, Sestamibi scan, Localization studies, Parathyroid
Esquema
Vol 215 - N° 5
P. 788-792 - mai 2018 Regresar al número
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- Discussion of “Dual energy computed tomography should be the first line preoperative localization imaging test for primary hyperparathyroidism patients”
- J. David Beatty
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