Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin - 19/04/17

Doi : 10.1016/j.jaci.2016.09.017

Patrick L.J.M. Zeeuwen, PhD ^a,^{^{∗
Co-first authors: These authors contributed equally to this work.}} , Thomas H.A. Ederveen, MSc ^b,^c,^{^{∗
Co-first authors: These authors contributed equally to this work.}}, Danique A. van der Krieken, MSc ^a,^{^{∗
Co-first authors: These authors contributed equally to this work.}}, Hanna Niehues, MSc ^a,^{^{∗
Co-first authors: These authors contributed equally to this work.}}, Jos Boekhorst, PhD ^b,^c, Sanja Kezic, PhD ^d, Daniëlle A.T. Hanssen, MSc ^a, Marisol E. Otero, MSc ^a, Ivonne M.J.J. van Vlijmen-Willems, BSc ^a, Diana Rodijk-Olthuis, BSc ^a, Denise Falcone, MSc ^a, Ellen H.J. van den Bogaard, PhD ^a, Marijke Kamsteeg, PhD, MD ^a, Heleen D. de Koning, PhD, MD ^a, Manon E.J. Zeeuwen-Franssen, PhD, MD ^e, Maurice A.M. van Steensel, PhD, MD ^f,^g, Michiel Kleerebezem, PhD ^h, Harro M. Timmerman, PhD ^c, Sacha A.F.T. van Hijum, PhD ^b,^c,^{^{‡
Co-senior authors: These authors contributed equally to this work.}}, Joost Schalkwijk, PhD ^a,^{^{‡
Co-senior authors: These authors contributed equally to this work.}}
^a Department of Dermatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
^b Center for Molecular and Biomolecular Informatics, Radboud University Medical Center, Nijmegen, The Netherlands
^c NIZO Food Research B.V., Ede, The Netherlands
^d Coronel Institute of Occupational Health, Academic Medical Center, Amsterdam, The Netherlands
^e Department of Dermatology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
^f Division of Cancer Science, School of Medicine and Division of Biological Chemistry and Drug Development, School of Life Sciences, University of Dundee, Dundee, United Kingdom
^g Institute of Medical Biology, A*STAR, Singapore
^h Wageningen University, Host-Microbe Interactomics Group, Wageningen, The Netherlands

	This study was funded by a TOP grant from the Netherlands Organization for Health Research and Development (ZonMw) (grant no. 91211052) and by a Hotel Technology grant from ZonMw (grant no. 435000002). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
	Disclosure of potential conflict of interest: P. L. J. M. Zeeuwen and J. Schalkwijk have received grants from ZonMW (grant nos. 91211052 and 435000002). The rest of the authors declare that they have no relevant conflicts of interest.

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