Isolated increased serum TSH response to TRH is prevalent in celiac disease and predicts poor response to treatment - 29/02/08
Maria Elisabetta Baldassarre [1],
Maurizio Delvecchio [1],
Margherita Fanelli [2],
Salvatore Stasolla [1],
Angelo Acquafredda [1]
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eliac disease (CD), or gluten-sensitive enteropathy, is an autoimmune disorder which involves the small bowel mucosa, sometimes associated with other autoimmune diseases. A supposed mechanism to explain this association is that gluten plays a key role in determining an immunological response directed against not only bowel mucosa cells but also beta-pancreatic cells, thyroid and other target-cells [1 et ]. Among these disorders, autoimmune thyroiditis occurs in 5-15% of celiac patients, both children and adults, more frequently with clinical signs of hypothyroidism rather than hyperthyroidism [1].
© 2005 Elsevier Masson SAS. Tous droits réservés.
Vol 29 - N° 10
P. 1063 - octobre 2005 Regresar al número
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