Cardiotoxicodynamics : Toxicity of Cardiovascular Xenobiotics - 29/07/15
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Résumé |
Maintaining adequate tissue perfusion depends on a variety of factors, all of which can be influenced by xenobiotics (substances foreign to the body, including pharmaceuticals, chemicals, and natural compounds). Volume status, systemic vascular resistance, myocardial contractility, and cardiac rhythm all play a significant role in ensuring hemodynamic stability and proper cardiovascular function. Direct effects on the nervous system, the vasculature, or the heart itself as well as indirect metabolic effects may play a significant role in the development of cardiotoxicity. This article is dedicated to discussion of the disruption of cardiovascular physiology by xenobiotics.
Le texte complet de cet article est disponible en PDF.Keywords : Cardiac electrophysiology, Antidysrhythmics, β-blockers, Calcium channel blockers, Cardioactive steroids, β-agonists, Methylxanthines, Central α2-agonists
Plan
Disclosures: None. |
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Funding Sources: None. |
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Conflict of Interest: None. |
Vol 33 - N° 3
P. 563-595 - août 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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