Comparison of the efficacy of diclofenac, acupuncture, and acetaminophen in the treatment of renal colic - 02/06/15
, Ferudun Koyuncu, MD b, İbrahim Buldu, MD c, Erdem Tekinarslan, MD d, Abdulkadir Tepeler, MD e, Tuna Karatağ, MD c, Mustafa Okan İstanbulluoğlu, MD c, Kadir Ceylan, MD aAbstract |
Objective |
The objective is to compare the analgesic effects of diclofenac, acetaminophen, and acupuncture in urolithiasis-driven renal colic pain relief.
Methods |
Renal colic patients were divided randomly into 3 groups. Patients in group I (n = 40) were treated with intravenous acetaminophen, those in group II (n = 41) with acupuncture, and those in group III (n = 40) with a 75-mg intramuscular injection diclofenac sodium. Visual analogue scale (VAS) and verbal rating scale (VRS) were used to assess pain intensity after 10, 30, 60, and 120 minutes.
Results |
No significant differences in baseline VAS or VRS were found with regard to age or sex. After 10 minutes, all 3 groups experienced a significant decrease in VAS and VRS scores, with the most drastic decrease occurring in group II. After 30 minutes, there was a significantly higher decrease in group III than in group I (P = .001). After 60 minutes, mean VAS scores of groups I and III (P = .753) were similar. The mean VAS score of group III was lower than that of group II (P = .013). After 120 minutes, the difference in the VAS scores was (P = .000) between groups I and II and between groups II and III. Yet, the VAS evaluation made after 120 minutes revealed statistically similar outcomes for groups I and III (P = .488). The statistical findings for VRS evaluations made after 10, 30, 60, and 120 were similar to those for VAS.
Conclusions |
In renal colic patients with a possible nonsteroidal anti-inflammatory drug and acetaminophen side effect risk, acupuncture emerges as an alternative treatment modality.
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| ☆ | Conflict of interest: none declared. |
Vol 33 - N° 6
P. 749-753 - juin 2015 Retour au numéro
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