Global Longitudinal Strain and Global Circumferential Strain by Speckle-Tracking Echocardiography and Feature-Tracking Cardiac Magnetic Resonance Imaging: Comparison with Left Ventricular Ejection Fraction - 04/05/15
Abstract |
Background |
Left ventricular (LV) ejection fraction (EF) is a routine clinical standard to assess cardiac function. Global longitudinal strain (GLS) and global circumferential strain (GCS) have emerged as important LV functional measures. The objective of this study was to determine the relationships of GLS and GCS by speckle-tracking echocardiography and featuring-tracking cardiac magnetic resonance (CMR) to CMR EF as a standard of reference in the same patients.
Methods |
A total of 73 consecutive patients aged 55 ± 15 years clinically referred for both CMR and echocardiography (EF range, 8%–78%) were studied. Routine steady-state free precession CMR images were prospectively analyzed offline using feature-tracking software for LV GLS, GCS, volumes, and EF. GLS was averaged from three standard longitudinal views and GCS from the mid-LV short-axis plane. Echocardiographic speckle-tracking was used from the similar imaging planes for GLS, GCS, LV volumes, and EF.
Results |
Feature-tracking CMR strain was closely correlated with speckle-tracking strain in the same patients: GLS, r = −0.87; GCS, r = −0.92 (P < .0001). End-diastolic and end-systolic volumes and EF by feature-tracking CMR were significantly correlated with standard manual tracing of multiple CMR short-axis images (r = 0.97, r = 0.98, and r = 0.97, P < .0001 for all). GLS and GCS by echocardiography and CMR feature-tracking were closely correlated with standard CMR EF: r = −0.85 and r = −0.95, respectively (P < .001). Global strain measures (in absolute values) were correlated with EF using the formula EF = 3(GLS) + 8% or EF = 2.5(GCS) + 8%.
Conclusions |
GLS and GCS by feature-tracking CMR analysis was a rapid means to obtain myocardial strain similar to speckle-tracking echocardiography. GLS and GCS were closely correlated with CMR EF in this patient series and may play a role in the clinical assessment of LV function.
Le texte complet de cet article est disponible en PDF.Highlights |
• | FT CMR is a rapid and reliable means to assess LV volumes and EF and global strain values. |
• | GCS and GLS can be similarly calculated by FT CMR and speckle-tracking echocardiography. |
• | LV GCS and GLS measured by any method correlate closely with EF. |
• | We propose two simplified formulas to estimate EF from global strain values that have potential clinical utility. |
Keywords : Magnetic resonance imaging, Echocardiography, Myocardial strain, Left ventricular function, Ejection fraction
Abbreviations : AUC, CMR, DICOM, EDV, EF, ESV, FT, GCS, GLS, LV, 3D, 2D
Plan
| Dr Saha was partly supported by the University of Pittsburgh and grants from Hjärt-Lungfonden, Sundsvall Hospital, and the Karolinska Institute of Stockholm. This study was supported by a software donation and technical support from TomTec Corporation (Munich Germany). Dr Gorcsan has received research support unrelated to this study from Biotronik, Medtronic, General Electric, Toshiba Medical, and St. Jude Medical. |
Vol 28 - N° 5
P. 587-596 - mai 2015 Retour au numéro
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