Diagnostic Applications of Nail Clippings - 29/03/15

Doi : 10.1016/j.det.2014.12.011

Sasha Stephen, MD ^a, Antonella Tosti, MD ^d,^⁎ , Adam I. Rubin, MD ^a,^b,^c
^a Department of Dermatology, Hospital of the University of Pennsylvania, 3600 Spruce Street, 2 Maloney, Philadelphia, PA 19104, USA
^b The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
^c Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
^d Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, 1600 Northwest 10th Avenue, RMSB 2023A, Locator Code R-250 Miami, FL 33136, USA

^∗Corresponding author.

Résumé

“Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the forensic applications of this easily obtained specimen. It reviews important considerations in optimizing specimen collection, processing methods, and efficacy of special stains in several clinical contexts. Readers will develop a greater understanding and ease of application of this indispensable procedure in assessing nail unit dermatoses.”

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Keywords : Nail clipping, Nail pathology, Onychomycosis, Melanonychia, Onychomatricoma, Subungual hematoma, Nail psoriasis, Nail cosmetics