Hepatectomy is a reasonable option for older patients with hepatocellular carcinoma - 13/02/15
, Jae Berm Park, M.D., Ph.D. a, Joon Hyeok Lee, M.D., Ph.D. b, Sung Joo Kim, M.D., Ph.D. a, Seung Woon Paik, M.D., Ph.D. b, Cheol Keun Park, M.D., Ph.D. cAbstract |
Background |
Hepatic resection is the main treatment for patients with hepatocellular carcinoma. However, surgery is generally stressful for older patients.
Methods |
Clinicopathologic data and outcomes after hepatic resection were retrospectively investigated for older patients with hepatocellular carcinoma. The younger group (n = 219) included patients aged 60 to 69 years, and the older group (n = 60) included patients >70 years of age.
Results |
Hepatitis B virus was more common in the younger group than in the older group (64.5% vs 28.8%, P < .001). The occurrence of pneumonia was higher in older group than in the younger group (10.0% vs 2.3%, P = .015), but postoperative complications and mortality were not significantly different between the 2 groups. There was no statistically significant difference in disease-free survival rates between the 2 groups.
Conclusions |
Although the incidence of postoperative pneumonia was higher in the older group than in the younger group, hepatic resection was justified for hepatocellular carcinoma in selected patients >70 years of age.
Le texte complet de cet article est disponible en PDF.Keywords : Older, Hepatic resection, Hepatocellular carcinoma, Hepatitis B virus, Postoperative mortality, Pneumonia
Plan
| Drs Jong Man Kim and Cho contributed equally to this work. |
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| The authors declare no conflicts of interest. |
Vol 209 - N° 2
P. 391-397 - février 2015 Retour au numéro
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