Genetic variants of inducible costimulator are associated with allergic asthma susceptibility - 05/02/15
Doi : 10.1016/j.jaci.2014.06.028
Anand Kumar Andiappan, PhD a, b, Sriram Narayanan, PhD a, Rachel A. Myers, PhD c, Bernett Lee, PhD a, Maartje A. Nieuwenhuis, PhD d, Alessandra Nardin, PhD a, Choon-Sik Park, MD e, Hyoung Doo Shin, PhD f, Jeong-Hyun Kim, PhD f, Harm-Jan Westra, PhD g, Lude Franke, PhD g, Tonu Esko, PhD h, Andres Metspalu, PhD h, Yik-Ying Teo, PhD i, j, Seang Mei Saw, MD, PhD j, Chiea Chuen Khor, PhD k, Jianjun Liu, PhD l, Gerard H. Koppelman, MD, PhD m, Dirkje S. Postma, MD, PhD d, Michael Poidinger, PhD l, John E. Connolly, PhD a, n, De Yun Wang, MD, PhD o, Olaf Rotzschke, PhD a, Maria A. Curotto de Lafaille, PhD a 
, Fook Tim Chew, PhD b
, Fook Tim Chew, PhD b a Singapore Immunology Network, Agency for Science, Technology and Research (A∗STAR), Singapore
b Department of Biological Sciences, National University of Singapore, Singapore
c Department of Human Genetics, University of Chicago, Chicago, Ill
d Department of Pulmonology and Tuberculosis, University Medical Center Groningen, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands
e Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
f Department of Life Science, Sogang University, Seoul, Korea
g Department of Genetics, University of Groningen, Groningen, The Netherlands
h Estonian Genome Center, University of Tartu, Tartu, Estonia
i Department of Statistics and Applied Probability, National University of Singapore, Singapore
j Saw Swee Hock School of Public Health, National University of Singapore, Singapore
k Infectious Diseases, Genome Institute of Singapore, A∗STAR, Singapore
l Human Genetics, Genome Institute of Singapore, A∗STAR, Singapore
m Department of Pediatric Pulmonology and Pediatric Allergology, University Medical Center Groningen, Beatrix Children's Hospital, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands
n Institute of Molecular and Cell Biology, A∗STAR, Singapore
o Department of Otolaryngology, National University of Singapore, Singapore
| These studies were supported by A*STAR/SIgN core funding, and grants SIgN-06-006, SIgN-08-020, and SIgN-10-029 and NMRC/1150/2008, Singapore. The Dutch Asthma GWAS (DAG) was supported by the Netherlands Asthma Foundation grant AF (AF 95.09, AF 98.48, AF 3.2.02.51, and AF 3.2.07.015) and a grant from the University Medical Center Groningen. |
|
| Disclosure of potential conflict of interest: B. Lee is employed by the Singapore Immunology Network. A Nardin is employed by, has received research and travel support from, and has a patent pending with the Singapore Immunology Network, Agency for Science and Technology and Research. D. S. Postma has received consultancy fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Takeda, and Teva and has received research support and lecture fees from Chiesi. D. Y. Wang has received research support from the Singapore Ministry of Education Academic Research Fund, Singapore Immunology Network, National Medical Research Council (NMRC) (Singapore), and the Agency for Science Technology and Research (A*STAR) (Singapore) and is employed by the National University of Singapore. F. T. Chew has received research support from the Singapore Ministry of Education Academic Research Fund, Singapore Immunology Network, National Medical Research Council (Singapore), and A*STAR (Singapore); has received consultancy fees from Sime Darby Technology Centre; and is employed by the National University of Singapore. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2014
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 135 - N° 2
P. 556 - février 2015 Retour au numéro
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