An Update on the Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk of Bronchopulmonary Dysplasia - 21/11/14
Doi : 10.1016/j.jpeds.2014.07.049
Lex W. Doyle, MD, FRACP 1, 2, ⁎ 
, Henry L. Halliday, MD, FRCP 3, Richard A. Ehrenkranz, MD 4, Peter G. Davis, MD, FRACP 1, 2, John C. Sinclair, MD 5, ∗
, Henry L. Halliday, MD, FRCP 3, Richard A. Ehrenkranz, MD 4, Peter G. Davis, MD, FRACP 1, 2, John C. Sinclair, MD 5, ∗ 1 Department of Obstetrics and Gynecology, The Royal Women's Hospital and University of Melbourne, Parkville, Australia
2 Clinical Sciences, Murdoch Children's Research Center, Parkville, Australia
3 Department of Child Health, Queen's University, Belfast, Northern Ireland
4 Department of Pediatrics, Yale University School of Medicine, New Haven, CT
5 Emeritus, Departments of Pediatrics, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
∗Reprint requests: Lex W. Doyle, MD, FRACP, Department of Obstetrics and Gynecology, The Royal Women's Hospital, 20 Flemington Road, Parkville, Victoria, Australia 3052.
Abstract |
Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.
Le texte complet de cet article est disponible en PDF.Keyword : BPD, CP, CS, RCTs, RD
Plan
| Supported by the National Health and Medical Research Council (NHMRC) of Australia (108700, 606789, and Centre of Research Excellence 1060733) and the Victorian Government's Operational Infrastructure Support Program. P.D. is supported in part by a Practitioner Fellowship (grant 1059111) from the National Health and Medical Research Council. The authors declare no conflicts of interest. |
© 2014
Elsevier Inc. Tous droits réservés.
Vol 165 - N° 6
P. 1258-1260 - décembre 2014 Retour au numéro
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