Changes in Muscle Strength in Patients With Statin Myalgia - 26/09/14
, Beth A. Taylor, PhD a, b, William Roman, BS a, Paul D. Thompson, MD aAbstract |
Statins can produce myalgia or muscle pain, which may affect medication adherence. We measured the effects of statins on muscle strength in patients with previous statin myalgia. Leg isokinetic extension average power at 60° per second (−8.8 ± 10.5N-M, p = 0.02) and average peak torque at 60° per second (−14.0 ± 19.7N-M, p = 0.04) decreased slightly with statin use, but 8 of 10 other variables for leg strength did not change (all p >0.13). Handgrip, muscle pain, respiratory exchange ratio, and daily activity also did not change (all p >0.09). In conclusion, statin myalgia is not associated with reduced muscle strength or muscle performance.
Le texte complet de cet article est disponible en PDF.Highlights |
• | We assessed muscle strength in patients with statin myalgia. |
• | We determined if statin myalgia is associated with changes in muscle performance. |
• | Myalgia is not associated with decrements in muscle strength or muscle performance. |
Plan
| This study was financially supported by Preventive Cardiology Residual Fund No. 121904. |
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| See page 1216 for disclosure information. |
Vol 114 - N° 8
P. 1215-1216 - octobre 2014 Retour au numéro
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