Probiotics and prebiotics in dermatology - 17/09/14

Doi : 10.1016/j.jaad.2014.04.050

Katherine L. Baquerizo Nole, MD ^a,^⁎ , Elizabeth Yim, MPH ^a, Jonette E. Keri, MD, PhD ^a,^b
^a Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida
^b Department of Dermatology, Miami Veterans Affairs Healthcare System, Miami, Florida

^∗Correspondence to: Katherine L. Baquerizo Nole, MD, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1321 NW 14th St, West Building, Ste 504, Miami, FL 33136.

Abstract

The rapid increase in the medical use of probiotics and prebiotics in recent years has confirmed their excellent safety profile. As immune modulators, they have been used in inflammatory skin conditions, such as atopic dermatitis. We review the literature regarding the use of probiotics and prebiotics in dermatology. Probiotics and prebiotics appear to be effective in reducing the incidence of atopic dermatitis in infants, but their role in atopic dermatitis treatment is controversial. Their role in acne, wound healing, and photoprotection is promising, but larger trials are needed before a final recommendation can be made.

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Key words : acne, atopic dermatitis, dermatology, prebiotics, probiotics, wound healing

Abbreviations used : AD, CDAD, IFN-γ, OR, PAD, RR, SCORAD