EPA-0022 – Diagnosis of diabetes and obesity have no impact on six month remission rates for depressed primary care patients - 01/08/14
Résumé |
Introduction |
Prior studies have demonstrated an inter-relationship between the diagnosis of diabetes, obesity and depression. Our data has demonstrated that baseline body mass index (BMI) was not predictive for clinical outcomes (remission at six months).
Objectives/Aims |
Our hypothesis was that obesity (BMI ≥30) and the diagnosis of diabetes in depressed primary patients would have no effect on depression remission rates six months after diagnosis.
Methods |
This study was retrospective analysis of 1, 894 primary care patients diagnosed with Major Depressive Disorder or Dysthymia with a PHQ-9 score of 10 or greater.
▪ | Outcome variable was clinical remission (PHQ-9 < 5) at six months. |
▪ | Logistic regression modeling included the demographic variables of age, gender, marital status, the clinical variables of BMI, baseline PHQ-9 score, diagnosis of diabetes (yes/no) and clinical diagnosis (recurrent or first episode of depression, or dysthymia). |
Results |
Odds ratio for clinical remission (PHQ-9<5) at six months in depressed primary care patients, by variable (N=1,894).
Figure 1Odds ratio for clinical remission (PHQ-9<5) at six months in depressed primary care patients, by variable (N=1,894).
Controlling for age, gender, marital status, race, clinical diagnosis and clinical site with logistic regression modeling.
Conclusions |
▪ | Baseline obesity was not an independent predictor for depression outcome at six months. |
▪ | Diagnosis of diabetes was not an independent predictor for depression outcome at six months. |
This data suggests that obesity and diabetes were not associated with worsening clinical outcomes in depression management.
Le texte complet de cet article est disponible en PDF.Vol 29 - N° S1
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