Topical pharmacotherapy for skin cancer : Part I. Pharmacology - 14/05/14
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Abstract |
Topical pharmacotherapy represents an effective alternative treatment for superficial skin cancer, primarily actinic keratoses and basal cell carcinomas. We provide an in-depth analysis of the pharmacologic aspects of available topical drugs for the treatment of primary skin tumors. In particular, we evaluate the mechanisms of action, formulations and indications, side effects, and contraindications of 5-fluorouracil, imiquimod, diclofenac, ingenol mebutate, and retinoids. Moreover, the characteristics of some investigational molecules (ie, resiquimod, piroxicam, dobesilate, and betulinic acid) are presented.
Le texte complet de cet article est disponible en PDF.Key words : 5-fluorouracil, betulinic acid, diclofenac, dobesilate, imiquimod, ingenol mebutate, piroxicam, resiquimod, retinoids, skin cancer
Abbreviations used : 5-FU, AK, BCC, BD, DHA, EPD, EQ, IM, IQ, LM, LSR, NSAID, RQ
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 70 - N° 6
P. 965.e1-965.e12 - juin 2014 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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