Mechanism of phosphatidylserine inhibition of IgE/Fc?RI-dependent anaphylactic human basophil degranulation via CD300a - 09/05/14
Doi : 10.1016/j.jaci.2014.03.029
Vito Sabato, MD a, b, Monica Boita, MS c, Saif Shubber, PhD d, Chris H. Bridts, MLT a, b, Akira Shibuya, PhD e, Luc S. De Clerck, MD, PhD a, b, Franco H. Falcone, PhD f, Didier G. Ebo, MD, PhD a, b 
a Faculty of Medicine and Health Sciences, Department of Immunology - Allergology - Rheumatology, University of Antwerp, Antwerpen, Belgium
b Immunology - Allergology - Rheumatology, Antwerp University Hospital, Antwerpen, Belgium
c Allergology and Clinical Immunology, University of Torino, Torino, Italy
d Division of Drug Delivery and Tissue Engineering, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom
e Faculty of Medicine, Division of Biomedical Sciences, Department of Immunology, University of Tsukuba, Tsukuba, Japan
f Division of Molecular and Cellular Science, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom
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| This research was funded by the Research Foundation Flanders/Fonds Wetenschappelijk Onderzoek (FWO). V.S. is a clinical researcher of the Research Foundation Flanders/Fonds Wetenschappelijk Onderzoek (FWO: 1700614N). D.G.E. is a senior clinical researcher of the Research Foundation Flanders/Fonds Wetenschappelijk Onderzoek (FWO: 1800614N). M.B. received a grant from the European Academy of Allergology and Clinical Immunology (EAACI Fellowship Award 2012). We also acknowledge the BMBS COST Action BM1007 “Mast Cells and Basophils – Targets for Innovative Therapies,” which facilitated their collaboration on this study and provided funds for an Short-Term Scientific Mission (STSM) for S.S. |
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| Disclosure of potential conflict of interest: V. Sabato has received research support from Fonds Wetenschappelijk Onderzoek and has received payment for lectures from Stallergenes. C. H. Bridts has patents with BD Biosciences and has received travel support from ThermoFisher Scientific. A. Shibuya has received research support from CREST/JST. D. G. Ebo has received research support from Fonds Wetenschappelijk Onderzoek, has received payment for lectures from Stallergenes and Thermofisher, and has patents with BD Bioscience. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2014
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
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