Impaired white-matter integrity in photosensitive epilepsy: A DTI study using tract-based spatial statistics - 29/04/14
, Bing Xie b, 2 , Peigang Lu a, 3 , Hua Feng c, 4 , Jian Wang b, 5 , Shaoji Yuan a, ⁎ Bienvenue sur EM-consulte, la référence des professionnels de santé.
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Summary |
Background and purpose |
The present study was designed to map alterations in brain white-matter in photosensitive epilepsy (PSE) by applying tract-based spatial statistics (TBSS) analysis.
Methods |
Diffusion tensor-imaging (DTI) data from MRI brain scans were collected from eight PSE patients and 16 gender- and age-matched non-epileptic controls using a SIEMENS Trio 3.0-Tesla scanner. For the white-matter analysis, DTI scans were processed using FSL software (index.html). Fractional anisotropy (FA) values in the PSE and control groups were compared using TBSS analysis corrected for multiple comparisons using threshold-free cluster enhancement.
Results |
Compared with the control subjects, the corpus callosum of PSE patients had significantly lower FA values.
Conclusion |
Our DTI study indicates that white-matter in the corpus callosum was abnormal in PSE patients, and that DTI methods can serve as useful non-invasive tools to evaluate white-matter changes in PSE patients.
Le texte complet de cet article est disponible en PDF.Keywords : Photosensitive epilepsy, White-matter, DTI, Tract-based spatial statistics
Plan
Vol 41 - N° 2
P. 131-135 - mai 2014 Retour au numéro
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