A total hip arthroplasty procedure can lead to significant perioperative blood loss due to bleeding from the medial circumflex pedicle. When either the anterior or posterior approach is used, haemostasis of this pedicle, which is typically performed with electrocautery without dissection, can be inadequate. The purpose of this study was to evaluate the efficacy of a novel surgical technique in which the pedicleis is directly ligated. A single-centre, single-surgeon prospective study was performed to compare pedicle ligation to electrocautery (control group). In the ligation group, the pedicle was identified in front of the upper-third of the quadratus femoris and ligated. The mean postoperative blood loss in the ligation group (293.4±34.8mL) was significantly less than in the control group (419.0±36.8mL) (P<0.05). Pedicle ligation is a simple procedure that reduces blood loss during total hip arthroplasty.