A review of toxicity from topical salicylic acid preparations - 14/03/14
Doi : 10.1016/j.jaad.2013.12.005
Raman K. Madan, MD a, b, Jacob Levitt, MD b, ⁎ 
a Beth Israel Medical Center, Mount Sinai Health System, New York, New York
b Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York
∗Reprint requests: Jacob Levitt, MD, Department of Dermatology, Mount Sinai School of Medicine, 5 E 98th St, 5th Floor, Box 1048, New York, NY 10029.
Abstract |
Topical salicylic acid is often used in dermatologic conditions because of its keratolytic, bacteriostatic, fungicidal, and photoprotective properties. The bioavailability of salicylic acid differs depending on the vehicle used and pH of transcellular fluids. Although rare, salicylic acid toxicity (salicylism) can occur from topical application. Physicians should be mindful of the potential for salicylism or even death from topically applied salicylic acid.
Le texte complet de cet article est disponible en PDF.Key words : ichthyosis, psoriasis, salicylic acid, salicylism, skin absorption, topical, toxicity
| Funding sources: None. |
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| Conflicts of interest: None declared. |
© 2013
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 70 - N° 4
P. 788-792 - avril 2014 Retour au numéro
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