Risk Factors for Short- and Long-Term Morbidity in Children with Esophageal Atresia - 07/03/14
Abstract |
Objective |
To describe short- (first year of age) and long-term (after 1 year of age) outcome in patients with esophageal atresia and identify early predictive factors of morbidity in the first month of life.
Study design |
Charts of children with esophageal atresia born January 1990 to May 2005 were reviewed. A complicated evolution was defined as the occurrence of at least 1 complication: severe gastroesophageal reflux, esophageal stricture requiring dilatations, recurrent fistula needing surgery, need for gavage feeding for ≥3 months, severe tracheomalacia, chronic respiratory disease, and death.
Results |
A total of 134 patients were included. Forty-nine percent of patients had a complicated evolution before 1 year of age, and 54% had a complicated evolution after 1 year. With bivariate analysis, predictive variables of a complicated evolution were demonstrated, including twin birth, preoperative tracheal intubation, birth weight <2500 g, long gap atresia, anastomotic leak, postoperative tracheal intubation ≥5 days, and inability to be fed orally by the end of the first month. After 1 year of age, the complicated evolution was only associated with long gap atresia and inability to be fed orally in the first month. A hospital stay ≥30 days was associated with a risk of a complicated evolution at 1 year and after 1 year of age (odds ratio, 9.3 [95% CI, 4.1-20.8] and 3.5 [95% CI, 1.6-7.6], respectively).
Conclusion |
Early factors are predictive of morbidity in children with esophageal atresia.
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Plan
The authors declare no conflicts of interest. |
Vol 156 - N° 5
P. 755-760 - mai 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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