How Are Childhood Thyroid Nodules Discovered: Opportunities for Improving Early Detection - 20/02/14
Doi : 10.1016/j.jpeds.2013.10.090
Anjuli Gupta, MD 1, ∗, Samantha Ly, MA 1, ∗, Luciana A. Castroneves, MD 1, ∗, Mary C. Frates, MD 7, Carol B. Benson, MD 7, Henry A. Feldman, MD 1, Ari J. Wassner, MD 1, 6, Jessica R. Smith, MD 1, 6, Ellen Marqusee, MD 6, 10, Erik K. Alexander, MD 6, 10, Justine Barletta, MD 8, Funmilayo Muyide 1, Peter M. Doubilet, MD, PhD 7, Hope E. Peters, MD 7, Susan Webb, RN 1, Biren P. Modi, MD 5, Harriet J. Paltiel, MD 2, Yolanda Martins, PhD 4, 10, Kelly Burmeister, PhD 4, Harry Kozakewich, MD 3, Monica Hollowell, MD 3, Edmund S. Cibas, MD 8, Francis D. Moore, MD 9, Robert C. Shamberger, MD 5, P. Reed Larsen, MD 6, 10, Stephen A. Huang, MD 1, 6, 10, ⁎ 
1 Thyroid Program of the Division of Endocrinology, Children's Hospital Boston, Boston, MA
2 Department of Radiology, Children's Hospital Boston, Boston, MA
3 Department of Pathology, Children's Hospital Boston, Boston, MA
4 Clinical Research Program, Children's Hospital Boston, Boston, MA
5 Department of Surgery, Children's Hospital Boston, Boston, MA
6 Thyroid Section of the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA
7 Department of Radiology, Brigham and Women's Hospital, Boston, MA
8 Department of Pathology, Brigham and Women's Hospital, Boston, MA
9 Department of Surgery, Brigham and Women's Hospital, Boston, MA
10 Dana Farber Cancer Institute, Boston, MA
∗Reprint requests: Stephen A. Huang, MD, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115.
Abstract |
In a retrospective analysis of childhood thyroid nodules, 18% were radiographic incidentalomas and 41% were discovered by a clinician's palpation; 40% were discovered by patients' families. The latter group had the largest nodules and highest rates of thyroid cancer metastasis, suggesting opportunities for earlier detection through annual well-child visits.
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| Supported by a donation from the Murray Family and the National Institutes of Health (DK076099 and DK007699). The authors declare no conflicts of interest. |
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Vol 164 - N° 3
P. 658-660 - mars 2014 Retour au numéro
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