Anti-tumor effect of paeonol via regulating NF-?B, AKT and MAPKs activation: A quick review - 18/02/14
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Abstract |
Paeonol, an active component extracted from Chinese herbs, Moutan cortex and Cynanchum paniculatum, has been characterized for its various biological activities, including sedation, hypnosis, anti-inflammatory, anti-allergic, and immunoregulation. Recently, paeonol was investigated to regulate the signalling pathways, including NF-κB, PI3K/PTEN/AKT and ERK/JNK/P38/MAPKs activations, which have been proposed to inhibit apoptosis and induce proliferation in human cancer. In this review, we summarized the literature documenting the involvement of the relationship between anti-tumor effect of paeonol and those signalling pathways.
Le texte complet de cet article est disponible en PDF.Keywords : Paeonol, Anti-tumor, NF-κB, PI3K/PTEN/AKT, ERK/JNK/P38/MAPKs
Plan
Vol 4 - N° 1
P. 9-14 - janvier 2014 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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