Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ?75 Years of Age - 12/02/14
, Ye Zhong, MD, MS a, Peter B. Berger, MD b, Gary Walford, MD c, Jeptha P. Curtis, MD d, Chuntao Wu, MD e, Ferdinand J. Venditti, MD f, Robert S.D. Higgins, MD g, Craig R. Smith, MD h, Stephen J. Lahey, MD i, Spencer B. King, MD jAbstract |
Several randomized controlled trials and observational studies have compared outcomes of percutaneous coronary interventions (PCIs) with drug-eluting stents (DESs) and coronary artery bypass grafting (CABG), but they have not thoroughly investigated the relative difference in outcomes for patients aged ≥75 years. In this study, a total of 3,864 patients receiving DES and CABG (1,932 CABG-DES pairs) with multivessel coronary disease were propensity matched using multiple patient risk factors and were compared with respect to 3 outcomes (mortality, stroke/myocardial infarction [MI]/mortality, and repeat revascularization) at 2.5 years with a mean follow-up of 18 months. The mortality rates (DES/CABG hazard ratio 1.06, 95% confidence interval 0.87 to 1.30) and the stroke/MI/mortality rates (DES/CABG hazard ratio 1.15, 95% confidence interval 0.97 to 1.38) for the 2 procedures were not significantly different. Repeat revascularization rates were significantly higher for patients who received DESs. In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
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| This work was supported by grant RC1HL099122 from the National Institutes of Health, Bethesda, Maryland. |
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| See page 808 for disclosure information. |
Vol 113 - N° 5
P. 803-808 - mars 2014 Retour au numéro
Article précédent
- Predictors of Reperfusion Delay in Patients With ST Elevation Myocardial Infarction Self-Transported to the Hospital (from the American Heart Association's Mission: Lifeline Program)
- David M. Shavelle, Anita Y. Chen, Ray V. Matthews, Matthew T. Roe, James A. de Lemos, James Jollis, Joseph L. Thomas, William J. French, ACTION-GWTG Investigators
- Aspiration Thrombectomy in Patients With ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (from the Acute Coronary Syndrome Israeli Survey 2010)
- Mady Moriel, Shlomi Matetzky, Amit Segev, Aaron Medina, Ran Kornowski, Haim Danenberg, Natalie Gavrielov-Yusim, Ilan Goldenberg, Dan Tzivoni, Shmuel Gottlieb, ACSIS and ACSIS-PCI investigators
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