Role of Infections - 06/02/14
Doi : 10.1016/j.ccm.2013.09.012
Kamen Rangelov, MD a, Sanjay Sethi, MD b, ⁎ 
a Pulmonary and Critical Care Medicine, University at Buffalo, SUNY, 3435 Main Street, Buffalo, NY 14214, USA
b Pulmonary, Critical Care, and Sleep Medicine, VA Western New York Healthcare System, University at Buffalo, The State University of New York, 3495 Bailey Avenue, Buffalo, NY 14215, USA
∗Corresponding author.
Résumé |
This article represents a review of the current literature on the role of infection in the pathogenesis of chronic obstructive pulmonary disease (COPD), in stable disease, exacerbations, and pneumonia. It outlines the complex interactions between respiratory pathogens and host immune defenses that underlie the clinical manifestations of infection in COPD.
Le texte complet de cet article est disponible en PDF.Keywords : Infection in COPD, Airway colonization, Chronic infection, New strain exacerbations, Pneumonia and COPD, Innate immunity in COPD, Virulence factors, Vicious-circle hypothesis
Plan
| Funding Sources: S. Sethi, supported by VA Merit Review and NHLBI. K. Rangelov, Nil. |
|
| Conflict of Interest: The authors declare no conflict of interest. |
© 2014
Elsevier Inc. Tous droits réservés.
Vol 35 - N° 1
P. 87-100 - mars 2014 Retour au numéro
Article précédent
- Cellular and Molecular Mechanisms of Chronic Obstructive Pulmonary Disease
- Peter J. Barnes
- Comorbidities and Systemic Effects of Chronic Obstructive Pulmonary Disease
- Gourab Choudhury, Roberto Rabinovich, William MacNee
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?