Use of Magnetic Resonance Elastography to Assess Hepatic Fibrosis in Children with Chronic Liver Disease - 18/12/13
Doi : 10.1016/j.jpeds.2013.07.050
Stavra A. Xanthakos, MD, MS 1, ⁎ 
, Daniel J. Podberesky, MD 2, Suraj D. Serai, PhD 2, Lili Miles, MD 3, Eileen C. King, PhD 4, William F. Balistreri, MD 1, Rohit Kohli, MBBS, MS 1
, Daniel J. Podberesky, MD 2, Suraj D. Serai, PhD 2, Lili Miles, MD 3, Eileen C. King, PhD 4, William F. Balistreri, MD 1, Rohit Kohli, MBBS, MS 1 1 Steatohepatitis Center, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
2 Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
3 Department of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
4 Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
∗Reprint requests: Stavra A. Xanthakos, MD, MS, Cincinnati Children's Hospital Medical Center, MLC 2010, 3333 Burnet Ave, Cincinnati, OH 45229.
Abstract |
Management of pediatric chronic liver disease is limited by lack of validated noninvasive biomarkers of histologic severity. We demonstrate that magnetic resonance elastography is feasible and accurate in detecting significant hepatic fibrosis in a case series of 35 children with chronic liver disease, including severely obese children.
Le texte complet de cet article est disponible en PDF.Keyword : ARFI, AUROC, BMI, MRE, NAFLD, NASH, ROI, US, TE
Plan
| Supported by National Institutes of Health (NIH; K23DK080888 [to S.X.] and K08DK084310 [to R.K.]) and the National Center for Research Resources and the National Center for Advancing Translational Sciences (8 UL1 TR000077-04). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. D.P. received travel reimbursement from GE Healthcare. The other authors declare no conflicts of interest. Dr Ehman (in the Acknowledgments) and the Mayo Clinic have licensed intellectual property and a financial interest in MRE technology. |
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Vol 164 - N° 1
P. 186-188 - janvier 2014 Retour au numéro
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