Usefulness and limitations of rapid urine dipstick testing for joint-fluid analysis. Prospective single-center study of 98 specimens - 28/11/13
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Abstract |
Objective |
To evaluate the diagnostic performance of rapid urine reagent strip testing of joint fluid in separating mechanical from inflammatory disease.
Methods |
In a prospective single-center 12-month study of joint fluid specimens, leukocyte esterase reagent strip testing (LERST) was compared to leukocyte counts used as the reference standard. Leukocyte counts greater than 2000/mm3 were taken to indicate inflammation. Reproducibility of LERST was evaluated by testing 73 specimens twice and computing Cohen's kappa coefficient.
Results |
Ninety-eight joint fluid specimens (26 with mechanical and 72 with inflammatory characteristics) were evaluated. LERST had 79.2% sensitivity, 92.3% specificity, 96.6% positive predictive value, 61.5% negative predictive value, a positive likelihood ratio of 10.3, and a negative likelihood ratio of 0.23. The kappa coefficient was 0.70 (0.53–0.87). Two negative LERSTs a few minutes apart had 80% negative predictive value and a negative likelihood ratio of 0.08.
Conclusion |
LERST of joint fluid is a rapid means of satisfactorily separating mechanical from inflammatory joint fluids.
Le texte complet de cet article est disponible en PDF.Keywords : Joint fluid, Urine dipstick, Reagent strip, Screening, Diagnosis, Inflammation
Plan
Vol 80 - N° 6
P. 604-607 - décembre 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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