Can the use of intraoperative intact parathyroid hormone monitoring be abandoned in patients with hyperparathyroidism? - 29/09/13
, Naomi Hayashida, M.D., Ph.D. a, Tatsuya Uga, M.D., Ph.D. b, Naoko Inokuchi c, Susumu Eguchi, M.D., Ph.D. aAbstract |
Background |
Ultrasound (US) and technetium-99m sestamibi scintigraphy (MIBI) are used to determine the localization of abnormal glands in cases of primary hyperparathyroidism (PHPT). Intraoperative intact parathyroid hormone (iPTH) monitoring is a reliable examination used to cure PHPT. The aim was to assess the necessity of intraoperative iPTH monitoring.
Methods |
Sixty patients were examined using preoperative MIBI and US. iPTH was measured at 3 time points: (1) at the start of surgery; (2) 10 minutes after gland resection; and (3) more than 60 minutes after surgery. We defined a decreased iPTH level as an iPTH measured 10 minutes after resection that was less than 50% of the preoperative level.
Results |
The iPTH of 55 patients with concordant lesions decreased to within the normal range more than 60 minutes after surgery.
Conclusions |
It is not necessary to monitor intraoperative iPTH when single concordant lesions are preoperatively identified on both MIBI and US.
Le texte complet de cet article est disponible en PDF.Keywords : Intraoperative intact parathyroid hormone monitoring, Primary hyperparathyroidism, Ultrasound, Technetium-99m sestamibi scintigraphy
Plan
| The authors declare no conflicts of interest. |
Vol 206 - N° 4
P. 574-577 - octobre 2013 Retour au numéro
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