The skin and hypercoagulable states - 17/08/13
Abstract |
Hypercoagulable states (HS) are inherited or acquired conditions that predispose an individual to venous and/or arterial thrombosis. The dermatologist can play a vital role in diagnosing a patient's HS by recognizing the associated cutaneous manifestations, such as purpura, purpura fulminans, livedo reticularis, livedo vasculopathy (atrophie blanche), anetoderma, chronic venous ulcers, and superficial venous thrombosis. The cutaneous manifestations of HS are generally nonspecific, but identification of an abnormal finding can warrant a further workup for an underlying thrombophilic disorder. This review will focus on the basic science of hemostasis, the evaluation of HS, the skin manifestations associated with hypercoagulability, and the use of antiplatelet and anticoagulant therapy in dermatology.
Le texte complet de cet article est disponible en PDF.Key words : anetoderma, antiphospholipid antibody syndrome, chronic venous ulcer, hemostasis, hypercoagulable states, livedo reticularis, livedo vasculopathy, purpura, superficial venous thrombosis, thrombosis
Abbreviations used : APC, APLA, APLS, CVU, DIC, DVT, HIT, HS, LMWH, LR, LV, PE, PF, SVT, TF, TTP, VTE
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 69 - N° 3
P. 450-462 - septembre 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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