Primary cutaneous B-cell lymphomas : Part I. Clinical features, diagnosis, and classification - 17/08/13
Abstract |
Primary cutaneous B-cell lymphomas (PCBCLs) are defined as lymphomas with a B-cell phenotype that present in the skin without evidence of systemic or extracutaneous disease at initial presentation, after adequate staging. In non-Hodgkin lymphomas, the skin is the second most common site of extranodal involvement after the gastrointestinal tract. PCBCLs are histologically very similar to their nodal counterparts, and these histologic similarities can lead to confusion about both therapy and prognosis. This article will summarize the clinical, pathologic, and diagnostic features of the 3 main types of PCBCL: primary cutaneous follicle center lymphoma, primary cutaneous marginal zone lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg-type, and the appropriate evaluation and staging procedures for each of these entities.
Le texte complet de cet article est disponible en PDF.Key words : histopathology, primary cutaneous B-cell lymphoma, primary cutaneous diffuse large B-cell lymphoma, primary cutaneous follicle center lymphoma, primary cutaneous marginal zone lymphoma, staging
Abbreviations used : DLBCL, FISH, FOX-P1, MALT, MUM1/INF4, PCBCL, PCDLBCL-LT, PCFCL, PCMZL, SALT
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
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Reprints not available from the authors. |
Vol 69 - N° 3
P. 329.e1-329.e13 - septembre 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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