Multiple samples improve the sensitivity for detection of mixed Mycobacterium infections - 15/08/13
Doi : 10.1016/j.tube.2013.06.002
Ying Peng a, c, Chongguang Yang b, c, Xia Li b, Tao Luo b, Fabin Li a, ⁎ 
, Qian Gao b, ⁎
, Qian Gao b, ⁎ a Tuberculosis Control Center of Heilongjiang Province, No. 40, Youfang Street, Harbin, Heilongjiang 150030, PR China
b Key Laboratory of Medical Molecular Virology, Institutes of Biomedical Sciences and Institute of Medical Microbiology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China
∗Corresponding author. Tel.: +86 21 5423 7195; fax: +86 21 5423 7971.∗∗Corresponding author. Tel.: +86451 55155411; fax: +86451 55157499.
Summary |
By using VNTR genotyping, mixed infections of Mycobacterium tuberculosis were detected in 11.2% of cases in a prospective study in Heilongjiang China, a setting with a high prevalence (87.5%) of Beijing family strains. If only one sputum sample had been collected, the study would have underestimated the fraction of mixed infections by 50%.
Le texte complet de cet article est disponible en PDF.Keywords : Mycobacterium tuberculosis, Mixed infections, Multiple sampling, Drug resistance
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© 2013
Elsevier Ltd. Tous droits réservés.
Vol 93 - N° 5
P. 548-550 - septembre 2013 Retour au numéro
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