The author uses the pulsed ablative CO₂ laser regularly for skin rejuvenation. This decision is based on the gold standard status of the CO₂ modality and an innovative aftercare treatment shown in the author’s practice to greatly reduce the complications of ablative pulsed CO₂ laser treatment. Depending on the patient and the severity of the skin condition, the author customizes each treatment, which may also include fractional CO₂ lasers, fat grafting, facelifting, or any combination of these techniques. This article presents a detailed description of the evolution of skin rejuvenation with lasers and the current role of lasers as an adjunct to face and necklift surgery.