Minocycline-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis - 24/04/13
, John M. Herre, MD b, c, Kimberly S. Salkey, MD a
Correspondence to: Melinda R. Mohr, MD, Eastern Virginia Medical School, Department of Dermatology, 721 Fairfax Ave, Suite 200, Norfolk, VA 23507.Abstract |
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare serious adverse effect associated with a variety of medications. We present a case of minocycline-induced DRESS syndrome, which resulted in acute renal failure, transient thyroiditis, and transaminitis, and a persistent lymphocytic myocarditis resulting in congestive heart failure. To our knowledge, this is the third reported case of minocycline-induced myocarditis. Additionally, we report successful plasmapheresis and rituximab treatment for minocycline-induced myocarditis associated with the DRESS syndrome.
Le texte complet de cet article est disponible en PDF.Key words : drug reaction, drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, hypersensitivity syndrome, myocarditis
Abbreviations used : ANA, CMV, DRESS, EBV, HHV, HIV
Plan
| Funding sources: None. |
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| Conflicts of interest: None declared. |
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| Reprints not available from the authors. |
Vol 62 - N° 2
P. 315-318 - février 2010 Retour au numéro
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