Salivary gland disorders are uncommon in the emergency department setting. Given the vast differential that spans infectious, autoimmune, neoplastic, and metabolic processes, they can pose a diagnostic challenge even to skilled clinicians. There is a paucity of evidence-based data regarding the management of these disorders with frequent incongruence between specific sources. Although by no means exhaustive or absolute, this article reconciles existing literature and serves as a concise and informative guide to salivary gland disorders encountered by the emergency care practitioner.