Extra-pulmonary tuberculosis developing at sites of previous trauma - 06/03/13
Doi : 10.1016/j.jinf.2012.08.010
David A. Barr a, ⁎ 
, Ashley M. Whittington a, Beth White b, Benjamin Patterson c, Robert N. Davidson a
, Ashley M. Whittington a, Beth White b, Benjamin Patterson c, Robert N. Davidson a a Dept. Infectious Diseases and Tropical Medicine, Northwick Park Hospital, 1053 Great Western Road, Harrow HA1 3UJ, UK
b Brownlee Centre for Infectious Diseases, Gartnavel General Hospital, Glasgow G12 0YN, UK
c NYU Langone Medical Centre, 550 First Avenue, New York, NY 10016, USA
Corresponding author. Tel.: +44 (0) 20 8869 2834, +44 (0) 7840 024124; fax: +44 (0) 20 8869 2836.Summary |
We describe five individuals in whom extra-pulmonary tuberculosis appeared to localise at a site of previous blunt injury. We review other similar case reports where preceding trauma was blunt and non-penetrating, and discuss a possible mechanism involving transport of mycobacteria in monocytes to sites of injury during “latent” tuberculosis infection. This challenges the conventional model proposed for mycobacteria dissemination in tuberculosis disease.
Le texte complet de cet article est disponible en PDF.Keywords : Tuberculosis, Extra-pulmonary tuberculosis, Pathogenesis, Trauma, Wounds and injuries
Plan
© 2012
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 66 - N° 4
P. 313-319 - avril 2013 Retour au numéro
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