Abdominal Pain and Functional Gastrointestinal Disorders in Children with Celiac Disease - 26/02/13
, Papa Adams, BS 1, Silvana Bonilla, MD 2, Diana Nichols-Vinueza, MD 3
Reprint requests: Miguel Saps, MD, Division of Pediatric Gastroenterology, Hepatology, & Nutrition, Ann & Robert H. Lurie Children’s Memorial Hospital, 225 East Chicago Avenue, Box 65, Chicago, IL 60611.Abstract |
Objective |
To assess whether patients with celiac disease (CD) are more likely than controls to develop abdominal pain (AP) and AP-associated functional gastrointestinal disorders (FGID) in long-term follow-up.
Study design |
In a retrospective study, data on children (3-22 years old) with CD diagnosed between 2000 and 2010 were obtained. Parents were contacted by telephone at least 6 months after the diagnosis of CD and invited to participate in the study. Consenting parents completed: (1) a telephone questionnaire on the presence of gastrointestinal symptoms; and (2) the parent report version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III for cases and selected controls.
Results |
Forty-nine cases (mean 11.3 years, 20 male participants) and 48 controls (mean 11.1 years, 24 male participants) were enrolled. Twelve children in the CD group (24.5%) and 7 children in the control group (14.6%) had AP at the time of the study (P = .3). Nine children in the CD group (18.3%) and 4 children in the control group (8.3%) met criteria for an AP-associated FGID according to the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (P = .23).
Conclusion |
It was found that children with CD and controls have a similar risk of AP and AP-FGIDs. Methodologic limitations prevent generalization of results, but large prospective studies should confirm the findings.
Le texte complet de cet article est disponible en PDF.Keyword : AP, AP-FGIDs, CD, EGD, FGID, IBS, QPGS-RIII, TTG
Plan
| The authors declare no conflicts of interest. |
Vol 162 - N° 3
P. 505-509 - mars 2013 Retour au numéro
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