Smooth muscle in tissue remodeling and hyper-reactivity: Airways and arteries - 02/02/13
Abstract |
Smooth muscle comprises a key functional component of both the airways and their supporting vasculature. Dysfunction of smooth muscle contributes to and exacerbates a host of breathing-associated pathologies such as asthma, chronic obstructive pulmonary disease and pulmonary hypertension. These diseases may be marked by airway and/or vascular smooth muscle hypertrophy, proliferation and hyper-reactivity, and related conditions such as fibrosis and extracellular matrix remodeling. This review will focus on the contribution of airway or vascular smooth dysfunction to common airway diseases.
Le texte complet de cet article est disponible en PDF.Keywords : Airway smooth muscle, Vascular smooth muscle, Asthma, Chronic obstructive pulmonary disease, Pulmonary hypertension, Animal models
Abbreviations : ASM, COPD, ECM, EMT, GAG, MCT, PAH, ⍺-SMA, VSM
Plan
Vol 26 - N° 1
P. 13-23 - février 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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