Regulation of GPCR-mediated smooth muscle contraction: Implications for asthma and pulmonary hypertension - 02/02/13
Corresponding author. Department of Physiology, University of Manitoba, JBRC, Rm 641, 715 McDermot Ave, Winnipeg, MB, Canada, R3E 3P4. Tel.: +1 204 391 3735.Abstract |
Contractile G-protein-coupled receptors (GPCRs) have emerged as key regulators of smooth muscle contraction, both under healthy and diseased conditions. This brief review will discuss some key topics and novel insights regarding GPCR-mediated airway and vascular smooth muscle contraction as discussed at the 7th International Young Investigators’ Symposium on Smooth Muscle (2011, Winnipeg, Manitoba, Canada) and will in particular focus on processes driving Ca2+-mobilization and -sensitization.
Le texte complet de cet article est disponible en PDF.Keywords : Calcium, Ca2+-mobilization, Ca2+-sensitization, CPI-17, Palmitoylation, ROCK
Plan
Vol 26 - N° 1
P. 121-131 - février 2013 Retour au numéro
Article précédent
- cAMP regulation of airway smooth muscle function
- Charlotte K. Billington, Oluwaseun O. Ojo, Raymond B. Penn, Satoru Ito
- Emerging airway smooth muscle targets to treat asthma
- Sana Siddiqui, Naresh Singh Redhu, Oluwaseun O. Ojo, Bo Liu, Nneka Irechukwu, Charlotte Billington, Luke Janssen, Lyn M. Moir
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