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Thirty-Day and 1-Year Outcomes of Emergency Department Patients With Atrial Fibrillation and No Acute Underlying Medical Cause - 24/11/12

Doi : 10.1016/j.annemergmed.2012.05.007 
Frank Xavier Scheuermeyer, MD, MHSc a, , Eric Grafstein, MD c, Rob Stenstrom, MD, PhD a, Grant Innes, MD d, Claire Heslop, MD, PhD a, Jan MacPhee, MD, MSc a, Reza Pourvali, MD a, Brett Heilbron, MD b, Lorraine McGrath, ARCT b, Jim Christenson, MD a
a Department of Emergency Medicine, St. Paul's Hospital and the University of British Columbia, Vancouver, British Columbia, Canada 
b Division of Cardiology, Department of Medicine, St. Paul's Hospital and the University of British Columbia, Vancouver, British Columbia, Canada 
c Department of Emergency Medicine, Mount St. Joseph’s Hospital, Vancouver, British Columbia, Canada 
d Division of Emergency Medicine, Foothills Hospital and the University of Calgary, Calgary, Alberta, Canada 

Address for correspondence: Frank Xavier Scheuermeyer, MD, MHSc

Résumé

Study objective

Atrial fibrillation is the most common dysrhythmia observed in the emergency department (ED), yet there is little research describing long-term outcomes after ED management. Our objective is to describe ED treatment approach, conversion success rates, ED adverse events, and 30-day and 1-year outcomes for a cohort of ED patients with atrial fibrillation and no acute underlying medical cause.

Methods

This retrospective cohort study used a database from 2 urban EDs to identify consecutive patients with an ED discharge diagnosis of atrial fibrillation from April 1, 2006, to March 31, 2010. Comorbidities, rhythms, management, and immediate outcomes were obtained by manual chart review, and patients with an acute underlying medical condition were excluded by predefined criteria. Patients were stratified into 5 groups according to ED management: electrocardioversion, chemical cardioversion, spontaneous cardioversion, rate control only, and no arrhythmia-specific treatment. To identify deaths, strokes, and ED revisits within 1 year, each patient's unique provincial health number was linked to the provincial vital statistics registry and the regional ED database. Primary outcome was the number of patients having either stroke or death of any cause at 30 days, stratified by treatment group.

Results

Of 927 consecutive eligible patients, 121 (13.1%) converted to sinus rhythm before ED intervention, 357 (38.5%) received ED rhythm control, and 449 (48.4%) did not receive rhythm control. Overall, 142 of 927 patients (15.3%) were admitted to the hospital at the index ED visit. At 30 days, 2 patients had a stroke and 5 died (combined outcome rate 0.8%; 95% confidence interval 0.3% to 1.6%). All 7 of these patients were admitted at the index ED visit.

Conclusion

In this large cohort of ED patients with atrial fibrillation and no acute underlying medical cause, the 30-day rate for stroke or death was less than 1%. Nearly 85% of patients—regardless of treatment approach or conversion to sinus rhythm—were discharged at the index ED visit, and none of these patients had a stroke or died at 30 days.

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Plan


 Please see page 756 for the Editor's Capsule Summary of this article.
 Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org). The authors have stated that no such relationships exist.
 Supervising editor: Keith A. Marill, MD
 Author contributions: FS conceived and designed the study. EG constructed data linkages for outcomes, and LM linked ECGs with patient data. FS, CH, JM, and RP conducted the chart review. BH provided chart review adjudication. FS and RS provided statistical analysis. FS drafted the article, and all authors contributed to its revision. FS takes responsibility for the paper as a whole.
 A P8DD8X2 survey is available with each research article published on the Web at www.annemergmed.com.
 A podcast for this article is available at www.annemergmed.com.
 Publication date: Available online June 26, 2012.


© 2012  American College of Emergency Physicians. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 60 - N° 6

P. 755 - décembre 2012 Retour au numéro
Article précédent Article précédent
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