Receptivity assessment of an ultrasonographic homogeneous endometrium in the late follicular phase of infertile women with natural cycles - 21/11/12
, Mengxun Chen, MM b, Jin Liu, MM b, Zhihong Fu, MD a, Xuemei Li, MB a, Chunrong Qin, MD a, Dayan Liu, MD a, Xuelian Tang, MM a
Reprints: Wenjie Zhu, MD, No. 3012, Fu-Qiang Rd., Shen-Zhen City, 518048, Guang-Dong province, ChinaRésumé |
Objective |
The purpose of this study was to assess the receptivity of the homogeneous endometrium in the late follicular phase in infertile women with natural cycles.
Study Design |
Twenty-eight infertile women with ultrasonographically homogeneous (group 1) or trilaminar (group 2) endometria in the late follicular phase underwent endometrial biopsies. Some molecular markers and development of pinopodes were evaluated.
Results |
In the late follicular phase, the mean level of vascular endothelial growth factor was significantly lower in group 1 than in group 2 (0.96 ± 0.37 marks vs 1.39 ± 0.46 marks; P = .010). In the mid luteal phase, a decreased leukemia inhibitory factor and integrin alpha v beta 3 levels were found in group 1 (1.58 ± 0.99 marks vs 2.59 ± 0.61 marks; 1.85 ± 0.72 marks vs 2.60 ± 0.73 marks; 1.92 ± 0.91 marks vs 2.83 ± 0.57 marks; P = .003; P = .011; P = .004). The rate of fully developed pinopodes in the mid luteal phase was significantly decreased in group 1 (P = .018).
Conclusion |
An ultrasonographically homogeneous endometrium in the late follicular phase was associated with poor receptivity in infertile women with natural cycles.
Le texte complet de cet article est disponible en PDF.Key words : homogeneous endometrium, pinopode, receptivity, vascular endothelial growth factor
Plan
| Supported by a grant for scientific research (grant no. 201002089) from the Shen-Zhen Bureau of Science and Technology. |
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| The authors report no conflict of interest. |
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| Cite this article as: Zhu W, Chen M, Liu J, et al. Receptivity assessment of an ultrasonographic homogeneous endometrium in the late follicular phase of infertile women with natural cycles. Am J Obstet Gynecol 2012;207:511.e1-7. |
Vol 207 - N° 6
P. 511.e1-511.e7 - décembre 2012 Retour au numéro
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