Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study - 21/11/12
, Alexandra S. Bullough, MBChB, FRCA c, Jocelynn T. Owusu, MPH a, Kimberley A. Tremblay, MS a, Cynthia A. Brincat, MD, PhD d, Mark C. Chames, MD d, John D. Kalbfleisch, PhD e, Ronald D. Chervin, MD, MS a
Reprints: Louise M. O'Brien, PhD, MS, Sleep Disorders Center, Department of Neurology, C728 Med Inn, Box 5845, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-5845Résumé |
Objective |
This study aimed to prospectively examine the impact of chronic vs pregnancy-onset habitual snoring on gestational hypertension, preeclampsia, and gestational diabetes.
Study Design |
Third-trimester pregnant women were recruited from a large, tertiary medical center from March 2007 through December 2010 and screened for the presence and duration of habitual snoring, as a known marker for sleep-disordered breathing. Clinical diagnoses of gestational hypertension, preeclampsia, and gestational diabetes were obtained.
Results |
Of 1719 pregnant women, 34% reported snoring, with 25% reporting pregnancy-onset snoring. After adjusting for confounders, pregnancy-onset, but not chronic, snoring was independently associated with gestational hypertension (odds ratio, 2.36; 95% confidence interval, 1.48–3.77; P < .001) and preeclampsia (odds ratio, 1.59; 95% confidence interval, 1.06–2.37; P = .024) but not gestational diabetes.
Conclusion |
New-onset snoring during pregnancy is a strong risk factor for gestational hypertension and preeclampsia. In view of the significant morbidity and health care costs associated with hypertensive diseases of pregnancy, simple screening of pregnant women may have clinical utility.
Le texte complet de cet article est disponible en PDF.Key words : gestational diabetes, gestational hypertension, preeclampsia, pregnancy, snoring
Plan
| L.M.O. has received equipment support from Philips Respironics Inc and has served on an advisory board for GlaxoSmithKline. R.D.C. receives educational grants from Philips Respironics Inc and Fisher Paykel Inc; is named in patents owned by the University of Michigan for signal analysis diagnostic algorithms and hardware relevant to the assessment and treatment of sleep disorders; and serves on the Board of Directors of the American Academy of Sleep Medicine. The other authors report no potential conflict of interest. |
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| Cite this article as: O'Brien LM, Bullough AS, Owusu JT, et al. Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study. Am J Obstet Gynecol 2012;207:487.e1-9. |
Vol 207 - N° 6
P. 487.e1-487.e9 - décembre 2012 Retour au numéro
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