A population-based study of the risk of repeat clinical chorioamnionitis in Washington State, 1989–2008 - 21/11/12
Résumé |
Objective |
Chorioamnionitis can cause severe complications for the infant; therefore, characterization of the risk of recurrence and identification of the factors that modify it are clinically relevant to pregnant women and their providers.
Study Design |
The risk of recurrence was examined in a retrospective population-based cohort study with the use of birth certificate and delivery hospitalization discharge data from Washington State for the years 1989–2008.
Results |
Women who had chorioamnionitis in their first deliveries were 3.43 times as likely to have chorioamnionitis in their second deliveries as were women who did not have chorioamnionitis in their first deliveries (95% confidence interval [CI], 2.67–4.42; P < .001). Smoking status modified this association (smokers: odds ratio, 1.38 [95% CI, 0.62–3.08]; nonsmokers: odds ratio, 3.80 [95% CI, 2.88–5.00]).
Conclusion |
These data provide strong evidence for the occurrence of repeat chorioamnionitis; the association is strongest in women who do not smoke during pregnancy.
Le texte complet de cet article est disponible en PDF.Key words : chorioamnionitis, intraamniotic infection, pregnancy complication, smoking
Plan
| The first 2 authors contributed equally to this article. |
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| Supported by National Institutes of Health training grant number TL1 RR025016 (T.R.K.). |
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| The authors report no conflict of interest. |
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| Reprints not available from the authors. |
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| Cite this article as: Cohen-Cline HN, Kahn TR, Hutter CM. A population-based study of the risk of repeat clinical chorioamnionitis in Washington State, 1989–2008. Am J Obstet Gynecol 2012;207:473.e1-7. |
Vol 207 - N° 6
P. 473.e1-473.e7 - décembre 2012 Retour au numéro
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