Nerve transfers have been performed for many years, but the technique is further developing and gaining increased recognition as a time-tested procedure. The original operations are continually modified to treat a wide variety of peripheral nerve injuries, and yield reliable results. In addition, nerve transfers can be used in conjunction with tendon transfers or nerve grafts in order to best treat a specific patient’s set of deficits. This review of nerve transfers briefly discusses the evolution of the technique, general principles, some specific transfers, post-operative rehabilitation, and their place on the reconstructive ladder.