Among the infectious diseases of the right hypochondrium, cholecystitis, cholangitis, and liver abscesses predominate. These are frequently encountered diseases, but they can still raise questions in daily practice. In this elaboration, we will thus address and illustrate: the major infectious diseases of the liver and gallbladder, and their radiological features; the potential interpretation problems and differential diagnoses; the diagnostic and therapeutic strategies used in imaging to manage infections of the right hypochondrium.